Background: Given the limitations associated with Chlorhexidine (CHX), the quest for an effective and safe anti-plaque agent has spurred the development of alternative products. Recent advances in alternative medicine have led to the introduction of various new herbal alternatives for the treatment of gingivitis. The present study clinically evaluated the effect of a herbal mouthwash consisting of green tea and chamomile tea combination on periodontal indices. Aim: The present study evaluated the comparative efficacy of novel herbal and CHX mouthwashes on the gingival health of healthy individuals. Materials and Methods: The present study was a randomized parallel group controlled trial. A group of 30 healthy subjects in the age group of 18-40 years received complete supragingival scaling at baseline. Pre-operative clinical parameters, including Plaque Index (PI), Gingival Index (GI), Probing Depth (PPD), and Clinical Attachment Loss (CAL), were documented prior to oral prophylaxis and again two weeks after the procedure. Subjects were then randomly divided into the two groups (15 in each group) and were randomly intervened with the two different mouthwashes: novel herbal mouthwash and CHX mouthwash. Variables were again recorded on the 14th day after the use of mouthwashes, and data obtained were subjected to statistical analysis. Results: There was no significant difference in the efficacy of novel herbal mouthwash and CHX mouthwash on plaque accumulation, gingival health, and oral hygiene status. Conclusion: Herbal mouthwashes can prove to be effective alternatives to CHX with fewer side effects.