Postoperative pain is common in various oral surgical procedures. This ranges from mild to severe depending on the extent of surgery and type of intervention. This pain is constant sometimes even after the analgesic administration. Therefore, this study was planned, outlined and conducted to assess the clinical efficiencies of Dylotop and Naproxen in controlling postoperative pain related to common oral surgical procedures. Materials and Methods: Total 60 patients were included in the study in the age range of 30-45 years. Randomization was done and patients were categorized into 2 groups. All Patients were recalled after 48 hours and 72 hours of intended oral surgical procedures. Patients were asked for pain and its associated considerations. Visual analog scale (VAS) was used to compute the degree and level of pain and its control. Group 1 consisted of 30 patients wherein Dylotop was utilized. In Group 2 patients, Naproxen was used on 30 patients. Statistical analysis was performed to outline the outcomes and results. P value less than 0.05 was taken as significant. P value less than 0.05 was taken as significant. Statistical Analysis and Results: Basic statistical analysis was done with SPSS software version 22 for Windows. Out of 60 studied patients, 41 were males and 19 were females. In Group 1; after 48 hours, 23 patients were exhibited satisfactory responses about pain control. 5 patients showed non- satisfactory responses. In Group 2; after 48 hours, 27 patients were showed satisfactory responses about pain control. 2 patients showed non- satisfactory responses. After 72 hours, 28 patients were exhibited satisfactory responses about pain control. 1 patient showed non- satisfactory responses. Here, p value was highly significant. The interpretations of ANOVA confirmed that level of significance (p value) was highly significant. Conclusion: Authors concluded that both of the experimented pain relievers are effective however; Naproxen was fairly superior in postoperative pain control when compared with Dylotop. Interpretations were statistically significant for non-satisfied cases in both the groups checked at both timings.