ISSN : 2663-2187

Congenital Adrenal Hyperplasia with Salt Wasting Crisis- A Case Report

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Madhu Manaswini, Shanthiramesh, Prithvi Raj, Jagdeep Ramesh
» doi: 10.33472/AFJBS.6.6.2024.7394-7397

Abstract

Congenital Adrenal Hyperplasia(CAH) is a recessive group of disorders transmitted autosomally, which is because of impaired cortisol synthesis. 21-Hydroxylase deficiency is the frequent of all the causes. Its onset is before birth usually. It should be identified & treated early to prevent its fatal effects. It can be presented in various forms.The presentation of each type varies depending on the type of enzymaticdeficiency.Infants present as classical form which is further divided as salt-wasting if there is mineralocorticoid deficiency and simple – virilizing if there is no deficiency of mineralocorticoidwhereas as others present as non classical form.This division of sub types is not useful clinically as the children with CAH may lose some extent of salt and their presentations might get overlapped. Clinical features may differ based on the type of CAH and child’s gender.It includes vomitingwhich leads to dehydration, salt wasting and death. In conditions of severe virilization,clitoromegalyis seen.There is either precocious puberty or failure of puberty,Hirsutism, irregular Menstruation, infertility. Here,I present a clinical case of one month old boy child with CAH-salt wasting type. I confirmed it on basis of increased 17-OHP levels we managed him symptomatically & necessary treatment given for lifelong basis .

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