ISSN : 2663-2187

Dietary effect of Alstonia Boonei stem bark extract on hematological profiles of Wistar albino rats after inducing oxidative stress with CCl4

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Robert I. Uroko , Victor E. Okpashi, Bayim P.R. Bayim , Anthony U. Onwuekwe , Kate M. Ucho and Igori Wallace
» doi: 10.33472/AFJBS.2.4.2020.45-56

Abstract

This study examined the dietary outcome of Alstonia boonei stem bark. A. boonei stem bark was extracted with ethanol after air-drying and grinding. Hematological indices of Wistar albino rats were impacted with carbon tetrachloride (CCl4 ). Eighteen male albino mice were used to check acute toxicity of the extract while 30 albino rats were used to examine the hematological functions – Packed cell volume (PCV), hemoglobin (Hb) concentration, total white blood cell (WBC) count, total red blood cell (RBC) count and platelet count.

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