ISSN : 2663-2187

Dosimetric Comparison of Different Radiotherapy Techniques for Scalp Sparing Whole Brain Radiotherapy

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May Gamal Ashour, Maha Kamaleldin, Neven Mahmoud, Emad Mohsen Barsoum, Ahmed Amin Abogabal
» doi: 10.33472/AFJBS.6.Si3.2024.217-224

Abstract

The brain is one of the most common sites of metastases from breast cancer primary. Whole-brain radiotherapy (WBRT) is mandatory in the treatment of some patients. The purpose of this study was to compare four different WBRT techniques and investigate their impact on the radiation dose received by the scalp and its sub-volumes. Material and methods: The simulation CTs of 10 different metastatic breast cancer patients who were previously treated with WBRT were used in this dosimetric study. Four different radiotherapy plans were designed for each patient. Results: All techniques showed comparable PTV coverage. The homogeneity index with OF-WBRT was 0.057±.09, 0.057±.0111 for FiF, and 058±.0114 for IMRT with no statistically significant difference (p = 0.407). IMRT resulted in a marked decrease in all scalp parameters with a statistically significant difference, with a little difference in the dose delivered to lateral subvolumes. When the scalp parameters were introduced in optimization with Six–fields IMRT the lateral and posterior scalp mean dose reduced significantly. Conclusion: Scalp-sparing intensity-modulated radiation therapy (IMRT) is achievable. The Average scalp dose can be reduced by around 45% without compromising PTV coverage.

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