To evaluate the effect of alternate occlusion on intermittent exotropia in children aged 3 to 8 years. Patients and Methods: This non-randomized, prospective study was conducted on 23 patients with intermittent exotropia who underwent alternate occlusion at the ophthalmology outpatient clinic of Menoufia University from April 2022 to February 2023. The eyes were alternately patched for 2 hours a day in cases with no dominant eye. In cases with a strongly dominant eye, the dominant eye was patched for 5 days a week and the non-dominant eye for 2 days a week. Results: For all children, with a mean age of 5.52±1.61 years, far control of deviation improved significantly after 3, 6, and 9 months of treatment using both control scales when compared to pretreatment (p=0.045, p=0.024, and p=0.012 for the 3-point scale, respectively) and (p=0.048, p<0.001, and p=0.009 for the 6-point scale, respectively). Near control showed no significant improvement after 3, 6, and 9 months of treatment using both control scales (p=0.565, p=0.229, and p=0.246, respectively, for the 3-point scale; p=0.592, p=0.409, and p=0.115, respectively, for the 6-point scale). The mean change in near and far exotropia angles improved significantly post-treatment compared to pretreatment (P<0.001 and P<0.05, respectively). The most improvement was achieved after 9 months in both angles. Stereopsis improved significantly after 9 months of treatment (p=0.012). Conclusions: Although it may be thought that occlusion disrupts fusion, thereby possibly reducing control, our results show that deviation angle, control, and stereopsis improve with a 9-month period of treatment. Alternate occlusion is a low-cost, non-invasive treatment with minimal side effects that can improve control and postpone the need for surgical intervention