ISSN : 2663-2187

Effect of Early Coma Arousal Therapy on Conscious Level Recovery and Cognition in Traumatic Brain Injury

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Mustafa Samir Mohamed Amein, Nawal Abd El-Raouf Abo Shady, Omar Abdel Aleem Abdel Moneim Ragab
» doi: 10.33472/AFJBS.6.Si3.2024.255-264

Abstract

Traumatic brain injuries (TBIs) can affect people of all ages and are a major cause of death and disability, with an incidence of ~10 million people worldwide. Coma arousal therapy of sufficient frequency, intensity and duration arise the brain by improving neuronal organization, increased dendritic branching and increased numbers of dendritic spines thus stimulating the reticular activating system and increasing the level of cognitive function. Purpose of the study: The purpose of this study was to investigate the effect of adding early comma arousal therapy to the conventional physical therapy program on conscious level recovery and cognition in traumatic brain injury. Subjects and methods: Thirty-two patients suffered from traumatic brain injury from both genders participated in this study. They were assigned randomly into two groups. Group A consisted of 16 patients (10 males and 6 females). Group B consisted of 16 patients (11 males and 5 females). Group A received early coma arousal therapy and conventional treatment of TBI. Group B received conventional treatment of TBI only. Glasgow coma scale (GCS) and Rancho los amigos scale (RLAS) were used to measure conscious level recovery and cognition respectively before starting the treatment, after 1 week, and after 2 weeks of interventions. Results: There were statistically significant differences in conscious level recovery and cognition after 1 and 2 weeks of intervention in favor of the study group (p<0.05). After 1 week of intervention, M±SD for GCS and RLAS were 11.94 ± 0.99 and 8.31 ± 0.70 in the study group, and 9.31±0.95 and 7.06±0.57 in the control group, respectively. After 2 weeks of intervention, M±SD for GCS and RLAS were 14.38±0.72 and 9.81±0.40 for the study group, and 10.31±0.95 and 7.5 ± 0.63 for the control group, respectively. Conclusion: early coma arousal therapy combined with the conventional physical therapy program was more beneficial in improving conscious level recovery and cognition than the conventional physical therapy only in traumatic brain injury

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