Halotherapy, also known as dry salt therapy, involves inhaling a negative ion-rich salt microclimate. Hypertonic saline solutions are used to help clear mucus in inflammatory respiratory conditions by dehydrating the periciliary layer. Objectives of the study are: To evaluate the level of airway clearance among patients with Respiratory problem in experimental and control group before administering halotherapy, To assess the effect of halotherapy on level of airway clearance in experimental group, To find out the association of airway clearance with selected demographic variables. A quasi-experimental study at IMS & SUM Hospital in Bhubaneswar, Odisha, involved 60 respiratory patients to assess the effect of halotherapy on airway clearance. The study used total enumerative sampling to form experimental (n=30) and control (n=30) groups. Data on socio demographics was collected using a self-structured schedule, and airway clearance was evaluated with the Airway Clearance Assessment Scale. Study resulted significant difference between the pre-test score and post test score after giving intervention (i.e. 3% hypertonic saline Nebulization) as evidenced by t test value at p=0.000 which is extremely significant. Considering the experimental group patients were reduced 6.4 symptoms score with t value =13.9,p value =0.000 which is highly significant but in control group reduction score was 2.2 with t value=6.5,p value =0.06 which is not statistically significant. The chi square analysis showed statistically significant association between airway clearance after giving Halo therapy. Halotherapy was effective in improving airway clearance in patients with respiratory issues. Future studies with larger samples and varied interventions could provide further insights