BACKGROUND: Trismus, or restricted mouth opening, is a common side effect of treatment for head and neck cancer. Trismus leads to several difficulties to the patients, like inability to open jaw while eating food, speaking, yawning. The patient usually Complaints of pain & tenderness in the face, more in the area in front of the ear, increases while Attempting to open the jaw, trying to eat food especially solid food. Physiotherapy plays an important role As a treatment of trismus. A 40-year-old Male with trismus was assessed using dial calliper for mouth opening and was treated using Physiotherapeutic approaches. Pre- and post intervention values were recorded. Physiotherapy interventions Included hot moist pack therapy, myofascial release, exercises for the temporomandibular joint (TMJ)Results: The results of this study indicated that after 20 days of physiotherapy treatment program the mouth opening increased significantly and there was reduction in VAS score in patients with trismus. The increase in mouth opening seems to be greater in the patient who was young in comparison with the two patients who were older. Conclusion: The present report emphasis on the Effect of 2 weeks of physiotherapy intervention using a combination of MT2 Blade Soft tissue mobilization and exercise has Benefited the patient in improving the mouth opening and overall quality of life.