Team building in health care provides opportunities for organizational improvements, increases employee and customer satisfaction, as well as improves patient outcomes. Team building is essential in every existing to develop and enhance open and positive communication among members and team motivation Aim: The aim of this study is to determine the effect of team building training program staff nurses' communication skills at Zagazig University Hospitals. Research Design: a quasi-experimental design was utilized. Setting: the study was conducted in Zagazig University Hospitals. Sample: a simple random sample (94) from staff nurses who worked in the previously mentioned setting.. Tools: three tools were used for of data collection, 1. Teambuilding knowledge questionnaire 2. Team building skill questionnaire and 3. Organizational communication questionnaire. Results there is a highly statistically significant difference between the studied nurses’ total team building knowledge pre and post program intervention as well as there was significant improvement in head nurses' communication skills mean score after the program implementation. Conclusion: there were statistically significant improvement on staff nurse's teambuilding knowledge and skills after program intervention. In addition, there was a statistically significant improvement in all types of organizational communication after program implementation. . Recommendations: Enhance assertive communication between workers and managers in order to identify areas for improvement, planning and carrying out organizational changes together