Understanding drug-receptor interaction is frequently achieved through the use of molecular docking, a recent drug designs technique. Imidazole compounds with substituted moieties were created for this investigation. Molecular docking tests were conducted on all substances to determine their ability to inhibit the 7K3N virus, NSP1 crystal structure. The findings of the molecular docking investigation indicated that every synthetic drug had a low binding energy and a strong affinity for the active pocket, making them potential effective inhibitors of the 7K3N virus