Scar post skin graft is common and affects psychosocial and overall quality of life (QOL) of individuals. The development of hypertrophic scars (HTS) following burns continues to be a significant concern for individuals who have been burned. Kinesio taping (KT) as well as myofascial release (MFR) demonstrated efficacy in enhancing the appearance in addition pliability of the scar but no studies were found to evaluate their effects on improving scar characteristics post skin graft. Objective: To evaluate the therapeutic effects of kinesio tape, myofascial release and combined effect of them on scars post skin graft Methods: Forty-five patients who had scars from skin grafts were chosen from El-Qasr Al Ainy hospital then divided into three groups of equal size using random allocation. They were between the ages of 20 and 45. Group A (KT group) got KT in addition to traditional physiotherapy (Deep friction massage as well as stretching exercises) for six weeks. Group B (MFR group) got MFR in addition to traditional physiotherapy (Deep friction massage and stretching exercises) for six weeks. Group C (KT and MFR group) received KT and MFR in addition to traditional physiotherapy (Deep friction massage and stretching exercise) for six weeks. Outcome measures: They were assessed with Modified Vancouver burn Scar assessment Scale (MVSS), A Schiotz tonometer device for scar characteristics and pliability, prior to and following six weeks of treatment. Results: Post-treatment, all three groups showed a substantial improvement in MVSS as well as scar pliability compared to their pre-treatment condition (p < 0.001). The percent of change in (MVSS) in group A, B and C was 16.76, 31.02 and 58.72% respectively. The percent of change in scar pliability in group A, B and C was 18.32, 43.34 and 57.83% respectively. Group C demonstrated a substantial improvement in MVSS as well as scar pliability compared to both group A (p < 0.001) and group B (p < 0.05). Conclusion: Using combined effect of kinesio tape and myofascial release is better in improving scar characteristics post skin graft