In Africa, a large population of people have been exposed to respiratory diseases as a result of Greenhouse Gases (GHG) generated during the burning of polluting fuels. Biofuels as an alternative source of clean energy emerged to ensure local and industrial users are free of air pollution. This paper elucidates the establishment of an Ethanol Micro-Distillery (EMD) plant in Ogbomosho Nigeria with a focus on the processes for ethanol production of 1,000 L per day capacity using cassava.