Sweet potatoes (Ipomoea batatas) are nutrient-dense root vegetables renowned for their high content of essential vitamins, minerals, fiber, and antioxidants. This study explores the health and therapeutic benefits of sweet potatoes, emphasizing their potential for enhancing overall health, regulating blood sugar levels, supporting immune function, and promoting cardiovascular health. The anti-inflammatory and antioxidant properties of sweet potatoes make them a valuable dietary component for preventing and managing chronic diseases such as diabetes, heart disease, and cancer. To investigate these benefits, we incorporated sweet potatoes into the diet of experimental Wistar rats, enriching their feed with boiled and grilled sweet potatoes. The rats' hematological parameters were closely monitored to assess the impact of the fortified diet. Our findings indicated significant improvements in red blood cell indices and white blood cell counts, suggesting enhanced oxygen-carrying capacity and immune response. Additionally, the study provided insights into the metabolic and immunomodulatory effects of sweet potatoes, highlighting their potential for therapeutic applications. The results demonstrated the importance of sweet potatoes as a functional food with significant health benefits. By providing a comprehensive understanding of their impact on health, this research supports the inclusion of sweet potatoes in both human diets and scientific studies aimed at improving health outcomes and disease prevention.