Pot experiments were conducted at a sandy soil in West Nubariya, Behayira Governorate, Egypt, to investigate the effect of saline water on the growth of tomato cultivars. Eleven cultivars of tomato (102, Pitobrid, 186, Nivert.737, 449, Nora.765, Logian, Darian.42, Privio, Thoria, 023) are irrigated with saline water. Saline irrigation water was prepared from mixtures of NaCl and CaCl2 pure salts (2:1, w/w) at the levels; none saline water, 2000, 3000 and 4000 ppm. The obtained data revealed that the applications of saline water (2000, 3000, and 4000 ppm) significantly decrease the either shoot or roots of tomato cultivars compared with control treatment. Maximum shoot of tomato cultivars is achieved with the application of non-saline water. Also, the obtained data showed that cultivars of tomato can be descending according to salinity tolerance as: 102 > Pitobrid > 186 > 449 > Nivert737 > Nora 765 > Logian > Darian 42 > Privio > Thoria > 023. The data showed the differences of Na+ and Cl- content in shoot of tomato cultivars were significant and increased with increasing application rates of saline water. The highest content of sodium chloride was found in “023” tomato cultivar, which is sensitive to salinity.