ISSN : 2663-2187

Evolutionary Immunology of Animal Hosts Unravelling the Coevolutionary Dynamics Between Host Immune Systems and Microbial Pathogens in Natural Populations

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Dr. Abhay Ghatage, Ms. Jayashree Nanaware, Dr. Rahul Sonavale
ยป doi: 10.33472/AFJBS.6.Si2.2024.2521-2530

Abstract

The study of the complex interactions between microbial pathogens and host immune systems, or "evolutionary immunology," sheds light on the coevolutionary processes that influence pathogen evasion tactics and immunological responses in wild populations. This abstract explores the evolutionary arms race between infections and hosts, emphasising the adaptive processes that fuel virulence and host immunity in microorganisms. By employing an integrative methodology that incorporates concepts from immunology, microbiology, and evolutionary biology, scientists have successfully deciphered the intricate evolutionary paths of host-pathogen relationships. Through the study of natural populations in a variety of environments, including aquatic and terrestrial settings, scientists have learned more about the selection factors that influence genetic diversity and adaptability in diseases as well as hosts. Key themes explored include the role of genetic variation in host susceptibility to infection, the evolution of immune recognition and response pathways, and the emergence of novel virulence factors in microbial pathogens. Additionally, this abstract discusses the implications of evolutionary immunology for disease ecology, vaccine development, and public health interventions. Overall, this abstract underscores the importance of understanding the coevolutionary dynamics between hosts and pathogens in elucidating the evolutionary trajectories of immune systems and microbial pathogens in natural populations

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