Thermophysical parameters such as density (p) of binary liquid mixtures of Anisole (methoxy benzene) with 2 -Methoxy ethanol, 2-Ethoxyethanol, and 2-Butoxy Ethanol have been calculated at temperatures of 303.15 K, 308.15 K & 313.15 K and speed of sound (u) measured at 303.15 K, 313.15 K. The excess molar volumes (VE) and excess isentropic compressibilities (κsE) of all the studied temperatures have been determined using the data measured from density and speed of sound. Redlich-Kister polynomial equation was fitted to the calculated VE and κsE values. Additionally, the estimated speed of sound data were compared with Jacobson's Free Length theory (FLT), and Schaff's Collision factor theory (CFT) to test their predictive capability. The results were analyzed in terms of physicochemical interactions occurred due to the solute- solvent components in the binary liquid mixtures. The existence of hydrogen bonding between Anisole and 2 -Methoxy ethanol, 2-Ethoxyethanol, and 2-Butoxyethanol was experimentally confirmed by using AT FT-IR Spectroscopic studies.