The study investigates various oils, revealing their diverse compositions and implications for cosmetic applications. Analysis elucidates the fatty acid composition, with pumpkin seed oil and safflower carrier oil exhibiting high levels of saturated fats, while fish oil and flaxseed oil emerge as rich sources of beneficial polyunsaturated fatty acids. Notably, Evening prime rose oil demonstrates superior stability with the lowest peroxide value (11.97 meq/1000g). Correlation analysis unveil strong positive correlations between oils like algal oil and flaxseed oil (0.958) and hemp seed oil and watermelon seed oil (0.990), indicating similar compositions. Induction times and kinetic parameters highlight oil’s susceptibility to oxidation, with fish oil showing long induction times and relatively low activation energies, suggesting moderate stability. Hydration values underscore oil’s moisturizing potential, with sea buckthorn oil and soyabean oil exhibiting consistently high hydration values, indicative of water absorption. Transepidermal Water Loss (TEWL) assessments unveil oil’s effects on skin barrier function, with algal oil and watermelon seed oil demonstrating lower TEWL values, suggesting enhanced moisturizing properties. This comprehensive analysis enhances our understanding of oil’s roles in skincare and guides the development of tailored formulations for optimal health and wellness.