ISSN : 2663-2187

Formulation and Evaluation of Herbal Bandage Containing Curcuma Longa, Azadirachta Indica and Tridax Procumbens for Wound Healing

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Mithun Maniyar, Snehal Chakorkar, Shrishail Gurgure, Vrunal More, Jitendra Kandle, Zadbuke Divya, Rutuja Mahamuni
» doi: 10.33472/AFJBS.6.4.2024.5894-5901

Abstract

Bandages are commonly used to cover small wounds, providing protection against foreign elements. However, these conventional bandages lack pharmacological benefits. This study aims to design, develop, and assess a herbal bandage containing curcuma longa, azadirachta indica, and tridax procumbens linn for treating cuts, wounds, and burns. The selected herbal drugs are recognized for their safety and minimal side effects compared to allopathic medicines. The herbal drugs were processed into a powder and mixed to create an ointment base, resulting in a medicated herbal bandage. The ointment was transferred on a bandage with cavity. The ointment exhibited a homogeneous mixture, smooth texture, and a greenish color, without any grittiness. A diffusion study confirmed the release of phytochemical components from the ointment. The antibacterial effectiveness of the formulations against staphylococcus aureus and pseudomonas aeruginosa was evaluated using the rapid turbidimetric assay. Comparative results with the marketed formulation Fradiomycin® indicated turbidity values of 0.158 and 0.144, respectively. In vitro anti-inflammatory activity was assessed using the proteinase inhibitory method and protein denaturation assay, alongside the standard drug Diclofenac sodium®. The herbal bandage displayed a % proteinase inhibition of 40.81% and a protein denaturation of 48.02%, indicating potential anti-inflammatory properties. This research highlights the development of a herbal bandage with potential wound-healing benefits, which has potential antibacterial and anti-inflammatory activities

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