ISSN : 2663-2187

FORMULATION AND EVALUATION OF NAPROXEN AND DOMPERIDONE MICROBEADS AS CONTROLLED DRUG DELIVERY SYSTEM

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Anshul Kumar, Vandana Sahani, Dr. Shivanand Patil
ยป doi: 10.48047/AFJBS.6.12.2024.3652-3667

Abstract

Any drug delivery system's two basic objectives are to deliver a therapeutic dose of the medication to the right location in the body and to reach and maintain the target drug concentration. This might be accomplished by using many dosage form-resembling beads that are separated into several smaller units, or "subunits," each of which displays a few desirable properties. Systems for delivering drugs in micro particulate form offer several established benefits over single unit dose forms. Making medication delivery microbeads is one of the methods that does not require using strong chemicals or high temperatures. The utilization of ionotropic gelation, emulsion gelation, polyelectrolyte complexation, and other standard procedures is included. The ionotropic gelation process has been the focus of most research when it comes to microbeads preparation because it is easier to prepare than other techniques. The foundation of the ionotropic gelation process lies in polyelectrolytes' capacity to counter link with ions and create a hydrogel sustained release formulation.

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