ISSN : 2663-2187

Formulation and Evaluation of Polyherbal Capsules for the Treatment of Poly Cystic Ovarian Syndrome (Pcos)

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Dr Nimita Manocha, Dr Pankaj Agrawal, Rahul Singh, Dr. Md Sajid Ali, Dr. Sandeep Gupta, Poonam Arora, Dr. Anjali ganjare, Dr. M. Vijaya Jyothi
ยป doi: 10.33472/Afjbs.6.6.2024.5879-5905

Abstract

Poly Cystic Ovarian Syndrome (PCOS) is a gynecological disorder with increasing presence in the women belonging to the reproductive age group with about 75% occurrence. With various studies, PCOS has shown impact on metabolic functioning also which was earlier only limited to reproductive functioning of women. The Objective of this study is to formulate herbal capsules using the herbal extract prepared by different herbs for the treatment of Poly Cystic Ovarian Syndrome. The capsules were formulated and then further evaluated. The collected herbs were first extracted using ethanol solvent and then further the extract was mixed with several excipients in different ratios based on increasing the ratio of the disintegrating agent to get fine granules. These granules were further made into the final end product which is the polyherbal capsules. These capsules were evaluated and tested. All the performed tests were evaluated and compiled. The performed tests showed all the parameters were in compliance as per the standard pharmacopoeias. The current research study was based on the role of medicinal herbs, namely, Bauhinia variegata, Emblica officinalis, Terminalia belerica, Terminalia chebula, Commiphora wightii, Cinnamon Cassia, Tribulus Terrestris, Hypericum perforatum, Commiphora molmol, Nigella sativa in the treatment of Poly Cystic Ovarian Syndrome. The study includes all the Phytochemical, Pharmacognostic, Rheological evaluation of the herbs and preparation of the end product polyherbal capsules. Also, the prepared formulation complies with all the standards as per Indian Pharmacopoeia and Ayurvedic Formulary.

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