Curcuma longa a member of the ginger family (Zingiberaceae), produces the rhizomes that are used to make turmeric. Rhizomes are subterranean horizontal stems that produce roots and shoots. It is becoming more difficult to control microbial infections and the healing of wounds due to the emergence and spread of antimicrobial medication resistance. The most potent and active ingredient in curcuma longa L., often known as turmeric, is curcumin, which has a long and proven history of use in medicine for skin care and human health. It has been suggested that curcumin possesses substantial antibacterial properties, and numerous efforts have been undertaken to ascertain its capacity to simultaneously regulate bacterial growth and facilitate wound healing. Curcumin formulations require addressing its limited water solubility, poor tissue absorption, and short plasma half-life due to its fast metabolism before they can be used as an effective wound healing treatment. To address the issue of curcumin's limited bioavailability, new curcumin nanoformulations have been developed. The medicinal uses of curcumin nanoformulations for antibacterial and wound-healing objectives are thus discussed in the current review.