One of the risk factors for periodontal diseases is obesity. The oral microbiology of obese individuals has only been the subject of a few studies. Periodontal diseases typically range from the mild, reversible infection known as gingivitis to the more severe, irreversible infection known as periodontitis, which causes the alveolar bone that supports the tooth to be destroyed and ultimately results in tooth loss. The aim of this study is to assess the levels of ICTP, TIMP-1 and MMP-8 as salivary biomarkers in obese patients with periodontitis or without diabetes.