The majority of DRPs happen at moments of transition in care, like admission, inpatient stay, and release. Adverse drug events, or unwanted and unpleasant drug side effects, are a significant source of avoidable iatrogenic morbidity and death and can be brought on by DRPs.Our aim is to study the effectiveness of physician facilitated pharmaceutical care in identification and resolution of drug related problems in General medical wards of a tertiary care hospital. For six months, prospective observational research was conducted. About the identification and resolution of DRPs in patients admitted to the 1000-bed tertiary care teaching hospital, Dr.Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, with physician assistance. The study enrolled 200 patients in total who fulfilled the inclusion criteria. To characterise the DRPs, a data collecting form was created utilising PCNE principles.Two hundred medical records in all were examined. According to the results, 153 out of 200 records had DRPs identified, while 47 records had none at all. Out of 153 records, 293 were found, of which 226 (77.13%) were attributed to ineffective therapy, 105 (36.18%) to drug treatment failure, and 66 (22.68%) to adverse events.This study shows that chemist engagement can be a useful tool in avoiding and resolving DRPs. In summary, our research demonstrates that DRPs are a major problem in hospitals, leading to co-morbidity, longer hospital stays, and higher cost burdens for the patients. According to the study, drug-related issues can be found and fixed by general practitioners (physicians) and chemists cooperating. This type of cooperation fills a crucial gap in the public health system, considering the substantial expense and disease burden associated with ADRs.