ISSN : 2663-2187

Insilico Molecular Docking Studies Of Novel Acridine Derivative Inhibiting Acetylcholinesterase For Alzheimer’s Disease Treatment

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Senthilraj R , Magesh M , Evelyn Sharon sukumaran1 ,Rameswari S3 Keerthika B2 , Bhuvaneshwari D2 , Pavithra T , Mahalakshmi D
» doi: 10.33472/AFJBS.6.10.2024.198-217

Abstract

Alzheimer's disease (AD) is a neurodegenerative brain disorder that causes diminished memory and cognitive decline, and it affects millions of people throughout the world. In particular, acetylcholinesterase (AChE) inhibitors have been studied as a means of studying the cholinergic system, since low acetylcholine levels, T protein aggregation, oxidative stress, inflammatory processes, and abnormal beta-amyloid, are all related to AD

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