Objective: The aim of this study was to examine the levels of psychological resilience, trait anxiety and hopelessness in male health care workers who do and do not exercise. Method: Relational research model, which includes comparison between variables and correlation type examinations, was used in the study. Brief Psychological Resilience Scale, Trait Anxiety Inventory and Beck Hopelessness Scale were used as data collection tools. In the analysis of the data, the Kolmogorov Smirnov normality test resulted in a normal distribution (p>.05), Independent Samples T-Test was used for pairwise comparisons, and Pearson correlation coefficient was used to reveal the relationship status. Results: While it was found that trait anxiety scores differed significantly between the exercising and non-exercising groups in the physician occupational group (p<.01), no significant difference was found between the groups in terms of psychological resilience and hopelessness scores (p>0.05). In the nurse occupational group, no significant difference was found between the groups who exercised and did not exercise in terms of trait anxiety, psychological resilience and hopelessness scores (p>0.05). While it was found that psychological resilience and trait anxiety scores differed significantly between the groups who exercised and did not exercise in the health technician occupational group (p<.01; p<.05), no significant difference was found between the groups in terms of hopelessness scores (p>0.05). While a strong negative correlation was found between the hopelessness scores of health care workers who exercised and their ages (p<.01), no significant correlation was found between the psychological resilience and trait anxiety scores and their ages (p>.05). Conclusion: It was concluded that the status of exercising made a difference in psychological resilience, trait anxiety and hopelessness in health care workers who did and did not exercise.