ISSN : 2663-2187

Isolation and characterization of MDR Pseudomonas aeruginosa lytic bacteriophages as a potential therapeutic alternative to traditional antibiotics

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Najwa, M. Alharbi and Mashayed, M. Ziadi
ยป doi: 10.33472/AFJBS.4.1.2022.56-66


The emerging resistance of pseudomonas aeruginosa to several antibiotic groups has resulted in difficulty in treating infected patients. As a result, bacteriophage therapy is now considered a promising treatment substitute. In this study, a novel bacteriophage, PaMAsh, with lytic activity against P. aeruginosa was isolated from wastewater. PaMAsh exhibited a moderate host range against the four tested bacterial strains, as well as high stability over a wide range of pH and temperature. Electron microscopy revealed that the PaMAsh phage belongs to the family Podoviridae.

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