The morphological and anatomical structure of the leaves of some plant species of the Genus Asanthophyllum C.A. Mey living in different habitats was studied and analyzed. We have studied the morphology of leaf hairs of 25 plant species, many of which were taken from 2-4 geographical points of their range, in order to determine the influence of environmental conditions on the type, morphology, and degree of drooping. As a result of the research, the following conclusions were made, in species A korshinskyi, A.borsezowii, A.elatius, A.cyrtostegium common in deserts and sec. Turbinaria - bare leaves are formed in Kopetdag, that the leaves of A.albidum, A.subglabrum, A.tenuifolium, A.stenostegium, A.adenophorum, A.krascheninikovii, A.brewibracteatum, A.aculeatum, A.borsezowii, A.serawchanicum, A.coloratum, A.jarmolenkii are pubescent only with simple hairs, and in A.pungens, A.lilacinum, A.pulchrum, A.korolkovii the leaves are pubescent with both simple and glandular hairs and trichrome. The shown differences of plants are associated with the ecological conditions of the place of growth.