ISSN : 2663-2187

New Analytical Method Development and Validation for Estimation of Dolutegravir Sodium in Synthetic Mixture by Using RP-HPLC

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Nitin Pandey, Nainsi Gupta, Anuradha Bhadauriya, Karan Patwa, Amit Maurya, Vishal Dubey,Megha Tiwari
ยป doi: 10.48047/AFJBS.6.Si3.2024.2584-2597

Abstract

Chromatography is a separation process that is achieved by distributing the components of a mixture between two phases, a stationary phase and a mobile phase. Those components held preferentially in the stationary phase are retained longer in the system than those that are distributed selectively in the mobile phase. The result obtained shows the developed methods to be Cost effective, Rapid (Short retention time), Simple, Accurate (the value of SD and % RSD less than 2), Precise and can be successfully employed in the routine analysis of these drugs in bulk drug as well as in tablet dosage form.

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