ISSN : 2663-2187

PASS As A Benchmark Among Outcome Measures In Rheumatoid Arthritis – How Well Does It Fare ?

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James E, Suseem S R
» doi: 10.33472/AFJBS.6.2.2024.774-782

Abstract

PASS acronym stands for Patient Acceptable Symptomatic State and is a simple global dichotomous question, the response to which determines the PASS status of a Rheumatoid Arthritis (RA) patient whether - satisfied or unsatisfied. An affirmative response indicates a patient perceived satisfactory state of this disease/symptoms while a negative response is an indication of patient dissatisfaction. RA symptoms are known to alleviate in remission hence a PASS positive response is also likely to be associated with clinical remission. Here we have assessed the 2 subsets of PASS patients i.e PASS positive and PASS negative and correlated the clinical reported outcomes with patient reported outcomes including PASS. Our study indicates a significant correlation between majority of clinical outcome measures and PASS states , however this was found not to be the same in the case of (Clinical Disease Activity Index) CDAI, (Rheumatoid Arthritis Disease Activity Index) RADAI and Visual Analogue Scale (VAS). Our study also investigated the persistence of symptoms in PASS positive status patients who were also identified to be in clinical remission. using a modified PASS questionnaire. 68% of the patients defined to be in clinical remission acknowledged the persistence of bothersome symptoms of the disease even in their remission state. Only 32% of the patients having clinically remission status were completely liberated from nagging RA symptoms. Hence, it is of therapeutic significance to address the needs of such patients though labelled to be in clinical remission and support them to achieve a complete remission including remission from the patient perspective.

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