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Can Combination Therapy Improve Outcomes in PDE5i-Refractory Erectile Dysfunction? A Systematic Review of Low-Intensity Extracorporeal Shockwave Therapy
Volume 8 | Issue - 8
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Influence of Storage Temperature on the Bond Performance of Universal Adhesives: A Narrative Review
Volume 8 | Issue - 8
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Effects of direct acting antivirals(DAAs)on cryoglobulinemia in patients infected with hepatitis C virus
Volume 8 | Issue - 8
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Effect of Education Sessions About Plastic Usage Hazards and Its Safe Disposal on Knowledge and Reported Practice of Female Employees at Port Said University: A Pre–Post Intervention Study
Volume 8 | Issue - 7
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Soil Quality Under a Cocoa-Based Agroforestry System With Associated Indigenous Tree Species In The Department Of Divo (Cote d’Ivoire)
Volume 8 | Issue - 7
Phytochemical screening andevaluation of the antidepressant activity of Mimusopselengi Linn. unripe Fruits in depressed mice
Main Article Content
Abstract
Background: MimusopselengiLinn.(ME) has been traditionally utilized for its antianxiety, cytotoxic, antimicrobial, and antioxidant properties. It is also used in cancer treatment and serves as a diuretic, anti- inflammatory, anti-HIV, and hypotensive agent. This study aims to assess the antidepressant activity of unripe fruits of Mimusopselengi Linn. in a mouse model of depression. Materials and Methods: Methanol extraction was conducted on unripe fruits of Mimusopselengi Linn. using a soxhlet apparatus. Mice were divided into five study groups a Normal Group, a Depression-Induced Control Group without treatment, a Standard Group (Imipramine,10 mg/kg,i.p) ,Mimusopselengi (200 mg/kg,p.o) and Mimusopselengi (400 mg/kg,p.o) for 21 days. Immobilization time was recorded in seconds and evaluated using the Tail Suspension Test (TST) and Forced Swimming Test (FST).
