Pomegranates (Punica granatum L.) is a deciduous tree from the Punicaceae family. Pomegranates peels are produced as a waste product during fruit processing and rich in components like antioxidants, organic acids, flavonoids and phenols. These bioactive compounds possess various medicinal properties. In this study, we used a variety of solvents to extract various compounds from the peel of pomegranates (Punica granatum L.). Alkaloids, flavonoids, carbohydrates, proteins, and polypehnols were identified by phytochemical screening in ethanolic, aqueous, and petroleum ether extracts which showed a significant antioxidant activity with highest value of antioxidants (0.014±0.01 mg/ml; IC50) observed in ethanolic extract. These extracts were analyzed by GC-MS, which revealed the presence of different secondary metabolites and phytochemical substances such as 5-(Hydroxymethyl) -2- (dimethoxy methyl) furan, 4H-Pyran-4-one 2 3-dihydro-3 5-dihydroxy-6 and Dimethyl phthalate etc.