In the present investigation, our objective was to analyse the possible anticataract efficacy of Mentha Spicata (MS) leaves by means of preclinical evaluation. This was accomplished by applying an in vitro model that utilized a single goat lens. Cataracts, which are characterized by the process of the lens becoming opaque, continue to be a prominent cause of vision impairment all over the world. Multiple sclerosis, which is well-known for its antioxidant and anti-inflammatory qualities, shows potential in avoiding or delaying the developing of cataracts. In our experimental setup, we first extracted active chemicals from the leaves of the MS plant, and then we applied those compounds to the lens of the goat under controlled conditions that were designed to simulate the formation of cataracts associated with oxidative stress. In order to evaluate the protective effects of multiple sclerosis (MS), a number of parameters, including lens opacity, oxidative stress markers, and histological alterations, were taken into careful consideration. The results of our study showed that the lenses treated with MS had a considerable reduction in lens opacity and a lessening of oxidative damage when compared to the lenses treated with controls. This suggests that MS has the potential to operate as a natural preventive treatment against the formation of cataracts. The findings of this study offer important insights into the therapeutic potential of MS leaves in preventing the formation of cataracts. These findings pave the way for additional clinical investigations as well as prospective opportunities in the pharmaceutical industry.