In recent times, there has been an increase in the validation of traditional medicinal practices involving medicinal plants, evident from numerous ethnomedicinal papers. Alstonia scholaris R. Br. (Apocynaceae), stands out among the various plants with promising ethnomedicinal properties, particularly in claims against Helminthes. Helminthes are primarily parasitic worms that typically infect animals including humans. The present study therefore aims to validate the ethnomedicinal claims of this plant against Helminthes. Moisture content, Ash & Extractive value, preliminary phytochemical screening and Anthelmintic activity of chloroform, ethanolic and aqueous extract was carried out on Pheretima posthuma against the reference drug Albendazole. The presence of carbohydrates, alkaloids, amino acids, flavonoids, tannin and protein was observed. Significant Anthelmintic properties were observed at higher concentration. Different extracts caused paralysis in 34.32 min, 17.29 min and 24.28 min whereas death time observed was 85.35 min, 33.32 min. and 42.31 min in 80 mg/ml concentration respectively against the reference drug at 40 mg/ml concentration has shown paralysis at 10.07 min and occurrence of death at 21.34 min. The results suggest that further studies may be carried out to isolate and evaluate the active constituents responsible for the activity.