To study the prevalence and patterns of prenatally diagnosed fetal congenital anomalies. Materials and methods: This investigation was conducted as a prospective cohort study in the department of Obstetrics and Gynaecology., All India Institute of medical Sciences (AIIMS) Raipur (CG), All antenatal women attending ANC at AIIMS, Raipur with their scan reports who were willing for regular follow up and giving consent to participate in the study were enrolled for the study over 1.5 years duration. All investigations were noted including double marker at 11 to 13+6 weeks gestation age (GA), ultrasonography anomaly scans at 11 to 13+6 weeks GA and TIFFA at 18-20 weeks GA and followed up till delivery. Results A total of 3830 antenatal cases were enrolled amongst them 215 fetus were diagnosed with congenital anomalies. Amongst them two were twin pregnancies. Total birth during this period was 1429 including live birth and still births. Thus, the prevalence of congenital anomalies is 1518 per 10,000 live birth Accounting for 15.18% and 95.35% patient were diagnosed antenatally and 4.6% postnatally. Maximum congenital anomalies were diagnosed at 14-20 weeks of gestation i.e. 46.5%.