Methicillin-resistant Staphylococcus aureus is a group of Gram-positive bacteria that are genetically distinct from other strains of Staphylococcus aureus. Postoperative MRSA infection can occur as surgical site infections (SSI), chest infections, or bloodstream infections (bacteraemia). MRSA is usually spread in the community by contact with infected people or things that are carrying the bacteria. Fifteen (15) swabs were taken from the post operative patients in the oral and maxillofacial surgery. The swabs were sent to the department of microbiology. These swabs were plated in nutrient agar, blood agar and mannitol salt agar. Bacterial morphology was identified by colony morphology and gram staining. Staphylococcus aureus species were identified from other staphylococcus species through coagulase tests. 15 swabs were collected out of which 8 swabs contained staphylococcal species. Out of 8 swabs 3 swabs contained staphylococcus aureus. Staphylococcus aureus were isolated from other staphylococcal species using coagulase tests. No MRSA was found. Patients who have a history of chemotherapy, immunosuppression, or recent hospital exposure prior to their surgery are at higher risk of developing MRSA-specific SSI and may benefit from prophylactic antibiotic therapy with appropriate coverage. Additionally, patients who develop MRSA SSIs are likely to have an extended postoperative inpatient stay.