Under the extreme development of climate change, the issue of urban heat islands (UHI) is an increasingly widespread concern in many countries worldwide, including Vietnam. In sustainable urban development, climate and environmental information are the most important factors, helping forecast climate change according to planning scenarios and providing recommendations and strategic directions in adjusting planning to minimize climate change. A practical method to study the complex mechanisms of urban climate formation at the urban planning stage is numerical simulation modeling, which assesses the impact of the UHI in relation to the area and evaluates the effectiveness of mitigation measures under different scenarios for that area. In this study, the authors evaluated the effectiveness of measures to minimize the impact of UHI, applied to the Van Phu urban area, Ha Dong Disc., using scenarios of positive change of green infrastructure improvement and increase in greenery in the area. Recommendations have been made to mitigate the UHI. Based on the heat regime simulation results, the solution of changing infrastructure and increasing green areas effectively minimizes the UHI phenomenon and ensures human thermal comfort in urban environments. Future research will focus on developing multivariate correlation regression models to evaluate the effectiveness of UHI mitigation through green infrastructure improvements.