Our world harbours a rich source of medicinal plants that are used in treating a wide range of diseases that have become a serious trait to mankind. Medicinal plants play a key role in the management of various diseases. Kigelia africana (K. africana), popularly known as the Sausage tree, is a multipurpose medicinal plant with many attributes and considerable potential. In African folklore and traditional medicine, the mysterious sausage tree, K. africana, has long been revered. Native American societies have long used this plant's unusual fruit, bark, and leaves as cultural artifacts and treatments for a wide range of illnesses. This extraordinary plant species has gained more attention recently, though not just as a representation of Africa's vast botanical diversity, but also as a reservoir of potential with a variety of uses that is just waiting to be discovered and realized. This has interested scientists, who have examined K. africana plant parts for their bioactivity, especially in developing nations where orthodox medicine are meager, expensive, or inaccessible. The various chemical constituents such as the naphthaquinones, iridoids, fatty acids, norviburtinal, sterols, lignans, terpenoids, and flavonoids are the essential building blocks responsible for its wide range of activities. Ethno-medicinal plant-use data in many forms has been heavily utilized in the development of formularies and pharmacopoeias, providing a major focus in global healthcare and contributing substantially to the drug development process. This review provides an insightful understanding on the ethnobotany, phytochemistry, medicinal uses, chemical constituents, pharmacological properties, and economic importance of K. africana in Africa specifically Nigeria. This plant has great potential to be developed as a drug by pharmaceutical industries but before recommending its use in modern systems of medicine, clinical trials are to be done.