Dental science has succeeded in using stem cells in advanced treatment methods with a creative approach compared to what was in the past. This has not only improved the treatment of oral and dental diseases, but has also created various advantages for the psychological aspect of man. It was from 1980 onwards that embryonic stem cells were used, and after that, pluripotent stem cells, which goes back to 2006. Also, mesenchymal stem cells, which can be obtained from bone marrow, fat, etc., were able to restore the health of the orodental region, especially the gingiva and periodontium tissues in patients, who are often seen with psychological issues including anxiety, depression, etc. In addition, stem cell therapies hold promise for treating diseases such as age-related jaw bone loss or tooth loss by differentiating MSCs into osteoblasts. Therapies in dentistry which are based on stem cells do not only seek physical health, but benefits both physical as well as mental health and create an overall better conditions for the patient. When the recovery period is shorter and faster, more peace of mind is created for the patients which is accompanied with an improved overall situation as compared to the traditional therapeutic methods.