Background: The Harmless Acute Pancreatitis Score (HAPS) is a scoring algorithm to identify patients with non-severe acute pancreatitis. This studyaimed to determinethe usefulness of HAPS in identifying patients who develop a mild AP and evaluate its predictability value. Methods: It was a prospective type of study conducted in Velammal Medical College, MGR University, Tamilnadu from January 2023 to January 2024 with a sample size of 50 patients. It included all first attack of acute pancreatitis of either gender over the age of 18 yrs. Patients with co-morbid disorders of CVS, RS, Renal system, anaemia, and smokers were excluded. HAPS, Ranson’s score, and CT-severity index scores were calculated for all the patients. The aetiology of Acute pancreatitis was determined as alcoholic, biliary, idiopathic, and the patients were followed up for 1-monthpost-discharge(need for readmission & the cause). Outcomes like duration ICU stay, local and systemic complications were also assessed. Results: The sensitivity, specificity, positive predictive value & negative predictive value of HAPS score was 92.85%, 81.81%, 86.67%, 90% respectively. The Cohen’s kappatest showing the measurement of agreement between Ranson’s score and HAPS was 0.1 with regards to the non-severe course and 0.3withrespect to the severe course. Fischer’s exact test with respect to a etiology was found to be significant in HAPS. Paired t-test with p-value <0.05 significance was performed on Haematocrit and Sr.creatin eat the time of admission, was found to be significant; BUN value at the time of admission was found to be not significant p=0.11.CTSeverityindex:mild (0-3): n=27 (54%), moderate (4-6): n=18 (36%), severe (7-10): n=5 (10%). Conclusion: HAPS is a highly sensitive & specific scoring algorithm that predicts a non-severe course of acute pancreatitis. HAPS might be an additional tool in the clinical assessment of acute pancreatitis, where early screening is important to treat the patients at an optimal level of care.