Purpose: This paper explores the function of Human Resources (HR) in steering the implementation of business sustainability models by elucidating how HR practices contribute to sustainable strategies, fostering a culture of innovation, and nurturing talent capable of driving long-term success within organizations. Design/Methodology/Approach: Employing a comprehensive literature review and interviews with HR leaders, this research adopts a descriptive approach and collects primary data from 252 HR professionals at various industries in Tamil Nadu through structured questionnaires. Findings: The findings reveal that HR acts as a catalyst in embedding sustainability into corporate culture, aligning employee skills with evolving business needs, promoting diversity, and fostering a resilient workforce. Research Limitations/Implications: However, this study acknowledges limitations, primarily focusing on established practices and the potential oversight of emerging trends or industry-specific variations. Future empirical studies are recommended to explore the effectiveness of HR-driven sustainable initiatives in diverse organizational settings Practical Implications: Highlight the necessity of integrating sustainability into HR strategies, encompassing talent acquisition, training, performance evaluation, and leadership development. It advocates for a holistic approach that intertwines sustainability goals with core HR functions to drive organizational success. Social Implications: By emphasizing the role of HR in fostering sustainability, this study highlights the broader societal impact of businesses. Organizations, through HR-led initiatives, can contribute positively to society by promoting ethical practices, reducing environmental footprints, and championing social responsibility. Originality: This paper contributes by showcasing HR’s influence on sustainable business models, offering insights into how HR practices can bolster organizational sustainability, and paving the way for further research and practical applications