Withania somnifera (L.) Dunal (also known as ashwagandha), a drug-producing plant, has been used for many years to treat a variety of chronic illnesses, including high blood pressure, arthritis, diabetes, Alzheimer's disease, and depression. W. Somnifera appears to possess anti-inflammatory, antioxidant, anticarinogenic, anti-diabetic, and anti-asthmatic effects similar to other medical plants. Somnifera is frequently linked to the ginseng plant because of its ability to lower stress, improve cognitive functions (including memory), and maintain a healthy immune system. Somnifera is frequently linked to the ginseng plant because of its ability to lower stress, improve cognitive functions (including memory), and maintain a healthy immune system. It encourages immune modulatory effects that help the adaptive immune systems humoral and cellular responses balance one another. Some of the active ingredients in w. Somnifera is believed to have medicinal benefits, including alkaloids, steroidal saponins, and steroidal lactones (including withanolides and withaferins). B. Somnifera is a safe and extremely effective treatment for a number of ailments, but its exact mechanism of action is still partially understood. One of the put-up theories states that W. Somnifera promotes cellular-mediated immunity or initiates chemical processes that aid in the production of therapeutic effects. Withania has been demonstrated to have a significant impact in immunological diseases by modifying a variety of cytokines, increasing T-cell proliferation, and enhancing macrophage activity. The current review is based on the most recent therapeutic effects of W. somnifera on a number of illnesses by affecting immunological markers and the active components of W. somnifera that cause these therapeutic actions. Additionally, there has been discussion of the chemical makeup of W. somnifera and its immunomodulatory function in type 2 allergic disorders