Morphometry is an important tool used in studies to understand the relationship of variables, such as age and sex, between organisms. Present study was carried out to ascertain sexual dimorphism of proximal epiphyseal breadth of tibia and develop appropriate standards for sex determination from tibia in central Indian population. Material and Methods: Present study was single-center, observational study, conducted in dry adult human tibia of known gender, regular in shape, from adult individuals of the Indian population, ten measurements were made on the joint face of the tibial plateau with help of digital vernier calipers. Results: 384 bones (192pairs) were in adequate condition and were therefore included in the study. The mean AP diameter for the medial condyle was more for right side than left while the transverse diameter was more for left side than right. The mean AP and the transverse diameter for the lateral condyle was greater on the left side. On comparing the two condyles it was seen that both anteroposterior and transverse measurement were greater for the medial condyle. No statistically significance (p >0.05) was seen on comparing the different parameters for both the sides. All parameters (APM, TM, APL, TL, ATI, PTI, API, AI, PI & TD) were larger in males as compared to females, difference was statistically significant. Conclusion: Total transverse diameter (TTD) and Antero posterior diameter of Lateral condyle (APLC) are considered as best parameters of sex determination. According to their percentage of accuracy, various parameters are arranged in the order of discrimination of sex from best to least as follows: TTD > APLC > APMC> TDMC = APD > TDLC > L.