The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the source of the current COVID-19 epidemic, which made it very challenging to find effective medicines. Conventional drugs and vaccines have raised concerns about reliability and safety. Treatment for “SARS-CoV-2” may include questionable medicines or vaccinations. Phytochemicals are a successful therapy for COVID-19, but further study is needed to identify anti-viral drugs. To investigate COVID-19 treatment with medicinal plants (MP), this study includes screening phytochemicals. The botanical elements were gathered from experts. The kind of secondary metabolites was then determined by a qualitative phytochemical screening (PS) of plant extracts. Plants such as “eucalyptus species, ginger, pepper, onions, berries, garlic, and lemons (primary components)” were regularly employed. PS was used in the discovery of the terpenoids, fatty acids, steroids, flavonoids, and saponins. By disrupting the entrance, replication, assembling, and discharges of viruses within their host targets, identified natural phytocompounds were shown to have the potential to demonstrate anti-viral effects. To find potential lead chemicals for anti-viral drugs during this time of fast development, the pharmaceutical sector specialized in extracts of phytochemicals from MP and aromatic herbs. We effectively combat SARS-CoV-2 and other coronaviruses, MP and phytocompounds have become crucial. The well-known natural goods spur people to work together and raise money to promote scientific research into additional phytochemicals from MP to develop an antiviral medication to fight COVID-19.