Depression, a pervasive mental health disorder, stands as the foremost cause of mental health-related disability globally. Affecting millions of people at any life stage, including the elderly, depression is a potentially life-threatening condition that can erode one's hopes, ambitions, and even the will to live, thereby exerting a profoundly adverse impact on society.Clinical studies have brought to light serious concerns about recurrence rates, side effects, and drug interactions despite the fact that there are many pharmaceutical therapies for depression. The creation of all-natural antidepressant chemicals originating from different plant sources has attracted increasing attention in recent years. One such plant is Habenaria intermedia D. Don, commonly known as Vriddhi. This orchid family member is a vital component of the famed polyherbal rejuvenator Chyavanprasha. Traditionally utilized in various herbal medicines for its restorative properties, Vriddhi's rejuvenating qualities make it a promising candidate for depression treatment.The trend towards using plant-based medications is gaining momentum, with extensive research exploring their effectiveness in treating various ailments, including neurological disorders like depression. The natural substances extracted from these plants exhibit encouraging results as potential antidepressants. The rejuvenating properties of Habenaria intermedia D. Don suggest its potential as a natural antidepressant. As the demand for plant-based therapies continues to rise, further research into the efficacy and mechanisms of such herbal treatments will be crucial in developing innovative and effective solutions for combating depression and enhancing mental well-being.