In this study, 46 individuals were examined for their prevalence, physical activity levels, and psychological factors associated with thyroid disorders and adhesive capsulitis (AC), a common shoulder condition. There is some evidence that thyroid disease is associated with AC, though research on the topic is limited. There is a higher prevalence of thyroid disorders in women (72.99%) than men, based on the sample, which is predominantly composed of individuals aged 50 and older (69.76%). The study found that 84.3% of participants had hyperthyroidism, suggesting that hyperthyroid women are more likely to seek treatment for AC associated with thyroid dysfunction. In terms of physical activity, hyperthyroid patients are inactive in large numbers, with longer disease durations being associated with higher rates. People with hyperthyroidism experience poor sleep quality, particularly those with chronic conditions. Additionally, individuals with thyroid dysfunction exhibited moderate to severe symptoms ofdepression and stress, suggesting psychological impact. Patients with hyperthyroidism as well as hypothyroidism often suffer from kinesiophobia, a fear of movement, which can exacerbate their musculoskeletal symptoms. Patients with AC and hypothyroid dysfunction showed functional limitations on the Disability of Arm, Shoulder, and Hand (DASH) scale. Thyroid disease type and TSH serum levels did not significantly correlate with quality of life (QoL) scores based on the SF-36 questionnaire. In contrast, chronic pain sufferers had a higher proportion of unhealthy individuals, indicating that their QoL could be negatively affected. There were higher levels of pain reported by hyperthyroidism patients, whereas there were higher levels of irritability among AC patients with thyroid dysfunction. As a result of this study, it is evident that thyroid disorders, AC, physical activity, and psychological factors interact in complex ways. It emphasizes the need for comprehensive management strategies to address the multifaceted effects of thyroid dysfunction on AC patients.