ISSN : 2663-2187

To study the efficacy of nalbuphine and fentanyl as adjuvants to epidural ropivacaine in lower abdomen and lower extremity surgeries in the patients attending tertiary care hospital, South India

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Dr. Malapolu Neeraja, Dr. Ch. Swarna latha, Dr. Kavati Hanumantha Rao, Dr. Durga Aparna Lakkoju
» doi: 10.48047/AFJBS.6.Si3.2024.2697-2704

Abstract

Introduction: Epidural adjuvants to local anaesthetics are used to enhance the quality and duration of surgical anaesthesia. The aim of this present study is to compare the clinical efficacy of Nalbuphine and Fentanyl as adjuvants to extradural ropivacaine for block characteristics and hemodynamic changes during lower abdominal & lower extremity surgeries. Specifically, the study compared Nalbuphine- 10mg and Fentanyl-50µg as adjuvants to extradural 0.75% (w/v) Ropivacaine in lower abdominal and lower extremity surgeries. Methodology: This study consisted of 50 patients undergoing elective lower abdominal and lower extremity surgeries aged between 18-60 years, either gender, belonging to ASA grade I and II randomly divided into two groups by lottery method. After taking written informed consent from Patients, Patients were put to extradural catheterization with 16/18 G size and given extradural anaesthesia. At the end of the study the data is analyzed statistically using SPSS 24.0 Version. Diagrammatic representation, Descriptive data given as Mean ± SD Continuous data analysis was done by t-test. Results: By administering these two drugs for two different groups of patients, their efficacy regarding duration of analgesia, onset of sensory and motor block, maximum level of blockade, sedation, drug related side effects viz. pruritus, nausea, vomiting, hypotension, etc., hemodynamic changes, time for regression of blockade, and postoperative analgesia were observed. Nalbuphine is found to give more duration of analgesia than Fentanyl.

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