ISSN : 2663-2187

Validation of therapeutic efficacy of polyherbal formulations using computational approach for type II Diabetes Mellitus

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Tamilselvi S1 , Veninthaa S J S1 , Saravana kumar N M2 , Varunsarvesh K S1 , Hariharan M1 , Praveen kumar P3
ยป doi: 10.48047/AFJBS.6.5.2024. 11037-11045

Abstract

Type 2 diabetes mellitus presents a significant health concern, often exacerbated by misconceptions and the prevalence of self-medication practices. Addressing this issue, our study introduces a novel polyherbal formulation for type 2 diabetes mellitus, comprising Trigonella foenum-graecum, Zingiber officinale, Allium sativum, Curcuma longa, Azadirachta indica, and Cinnamomum verum. Informed by an exhaustive literature review, these components were selected based on their recognized therapeutic properties. Leveraging in silico analyses and physicochemical assessments, we substantiate the efficacy and safety of our formulation. Furthermore, we have developed proprietary software to authenticate the formulation, providing a safeguard against the risks associated with uninformed selfmedication. To expand the scope of our investigation, we conducted comparative analyses with established market products, adhering to the standards outlined by the Ayurvedic Pharmacopoeia of India (API). Our research contributes to the advancement of evidence-based treatments for type 2 diabetes mellitus, offering a promising alternative grounded in scientific rigor and adherence to regulatory guidelines

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