Background: The term "postpartum haemorrhage" (PPH) refers to heavy bleeding after giving delivery. It is a serious condition that can be life-threatening. Objectives: The objectives of the study to assess the knowledge and practice of staff nurse on the prevention and management of PPH. Methods: Quantitative approach and a descriptive research design adopted for the study. The sample included 80 staff nurses from a selected hospital, chosen using convenient sampling. Results: The study shows that about 16.3% have low knowledge, around 33.7% have medium knowledge, and half have high knowledge. In contrast, only 8.7% show poor practices, while roughly 91.3% have good practices. This shows a big difference between what people know and how they use it. But because most people show good practices, it seems they can use what they know in real life. Conclusion: The study concluded that there is a significant gap between theoretical understanding and practical application, with most people showing high knowledge levels but only a smaller percentage demonstrating poor practices, the prevalence of good practice scores is commendable.