Background: The Neonatal Resuscitation Program (NRP) is a widely recognized and standardized training program developed by the American Academy of Pediatrics and the American Heart Association1. Aims: It aims to equip healthcare providers, including nurses, with the knowledge and skills necessary to resuscitate and stabilize newborn infants in the immediate postnatal period. This study aimed to evaluate the effectiveness of a newborn resuscitation skill training programme on the knowledge and skills of B.Sc. nursing students. Methodology: A pre-test/post-test design was employed. A Purposive sampling of B.Sc. nursing 3rd year students (n = 100) enrolled in Faculty of Nursing SGT University, Gurugram participated in the study. The training programme consisted of theoretical sessions, practical demonstrations, and hands-on practice sessions using simulation models. Result: The pre-test data indicates that the majority of subjects (70%) had Average knowledge, with only 22 % possessing good knowledge and only (8%) demonstrating Excellent knowledge. Conversely, the post-test data reveals that a vast majority of subjects (82 %) exhibited Excellent knowledge, while only 18% demonstrated Good knowledge. Analysis of the pre-test and post-test skill scores yielded a statistically significant "t" value of 21.30 (compared to a table value of 2.05, p < 0.05), leading to the rejection of the null hypothesis and acceptance of the research hypothesis. This indicates a significant difference between the mean pre-test and post-test skill scores of nursing students, demonstrating the effectiveness of the training programme in enhancing the skills of nursing students in newborn resuscitation. Conclusion: These findings suggest that the newborn resuscitation skill training programme was effective in enhancing the knowledge and skills of B.Sc. nursing students in this area. Future research could explore the long-term retention of these skills and their application in clinical settings.